BDBM521448 N-(1-(2-(4- Chloro-2- (pyrrolidin-1- yl)benzyl)-2,8- diazaspiro[4.5] decane-8- carbonyl)-1H- pyrazol-3-yl) methane- sulfonamide::US11149037, Example 63

SMILES CS(=O)(=O)Nc1ccn(n1)C(=O)N1CCC2(CCN(Cc3ccc(Cl)cc3N3CCCC3)C2)CC1

InChI Key InChIKey=WFVWDQHXCVCLOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521448   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521448(N-(1-(2-(4- Chloro-2- (pyrrolidin-1- yl)benzyl)-2,...)
Affinity DataIC50:  5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521448(N-(1-(2-(4- Chloro-2- (pyrrolidin-1- yl)benzyl)-2,...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent