BDBM521449 N-(1-(2-(2-(3- Oxa-8- azabicyclo [3.2.1]octan- 8-yl)-4- (trifluoromethyl) benzyl)-2,8- diazaspiro[4.5] decane-8- carbonyl)-1H- pyrazol-3-yl) methane-::US11149037, Example 74

SMILES CS(=O)(=O)Nc1ccn(n1)C(=O)N1CCC2(CCN(Cc3ccc(cc3N3C4CCC3COC4)C(F)(F)F)C2)CC1

InChI Key InChIKey=XTEAIQIFOCTDAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521449   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521449(N-(1-(2-(2-(3- Oxa-8- azabicyclo [3.2.1]octan- 8-y...)
Affinity DataIC50:  5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521449(N-(1-(2-(2-(3- Oxa-8- azabicyclo [3.2.1]octan- 8-y...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent