BDBM521458 N-(1-(2-(6- (Trifluoro- methyl) benzo[b] thiophene-2- carbonyl)-2,8- diazaspiro[4.5] decane-8- carbonyl)-1H- pyrazol-3- yl)acetamide::US11149037, Example 154

SMILES CC(=O)Nc1ccn(n1)C(=O)N1CCC2(CCN(C2)C(=O)c2cc3ccc(cc3s2)C(F)(F)F)CC1

InChI Key InChIKey=LAAFGMKMSVAKQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521458   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521458(N-(1-(2-(6- (Trifluoro- methyl) benzo[b] thiophene...)
Affinity DataIC50:  5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM521458(N-(1-(2-(6- (Trifluoro- methyl) benzo[b] thiophene...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent