BDBM521931 N-[5-[6-(difluoromethoxy)- 1H-indazol-5-yl]-1H-pyrazol- 4-yl]pyrazolo[1,5- a]pyrimidine-3-carboxamide::US11155557, Example 21

SMILES Nc1cc(OC(F)F)c(cc1C=N)-c1n[nH]cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=KTCIAOLTOISTRF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521931   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM521931(N-[5-[6-(difluoromethoxy)- 1H-indazol-5-yl]-1H-pyr...)
Affinity DataKi:  0.0500nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM521931(N-[5-[6-(difluoromethoxy)- 1H-indazol-5-yl]-1H-pyr...)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent