BDBM522051 N-[3-[6-(difluoromethoxy)- 3,4-dihydro-2H-1,4- benzothiazin-7-yl]-1-(2- oxotetrahydrofuran-3- yl)pyrazol-4-yl]pyrazolo[1,5- a]pyrimidine-3-carboxamide::US11155557, Example 141::US11155557, Example 142
SMILES FC(F)Oc1cc2NCCSc2cc1-c1nn(cc1NC(=O)c1cnn2cccnc12)C1CCOC1=O
InChI Key InChIKey=HKZKUYDLAQQSJQ-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 522051
Affinity DataKi: 0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair