BDBM523175 US11161855, Example 35

SMILES CCc1nc2cnc3ccsc3c2n1[C@H]1CC[C@H](CC#N)[C@H](O)C1

InChI Key InChIKey=VTRYKMIPNQEAPD-TYNCELHUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523175   

TargetTyrosine-protein kinase JAK2 [828-1132](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM523175(US11161855, Example 35)
Affinity DataIC50: >2.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [837-1142](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM523175(US11161855, Example 35)
Affinity DataIC50: <100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent