BDBM523903 2-amino-N-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidyl]-5-fluoro-pyridine-4-carboxamide::US11136325, Compound 5

SMILES Nc1cc(C(=O)NC2CCN(CC2)c2ncnc3[nH]cc(Cl)c23)c(F)cn1

InChI Key InChIKey=HMNJLWJEBCAECR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523903   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523903(2-amino-N-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50:  1.58nMAssay Description:ASK1 and ASK2 biochemical activities were also quantified using AlphaScreen technology which measures the degree of phosphorylation of a protein subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM523903(2-amino-N-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-...)
Affinity DataIC50:  3.72nMAssay Description:IMAP technology provides a homogeneous assay applicable to a wide variety of kinases, phosphatases, and phosphodiesterases without regard for substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent