BDBM525582 US11174250, Example 32::US11174250, Example Table4.4.2

SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cc(ccc1F)C(=O)NC1CCCCC1

InChI Key InChIKey=GLHJOTVYVUCLQO-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 525582   

TargetWD repeat-containing protein 5(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM525582(US11174250, Example 32 | US11174250, Example Table...)
Affinity DataKd:  6nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20?? C. for repeat studies and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534](Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM525582(US11174250, Example 32 | US11174250, Example Table...)
Affinity DataIC50:  332nMAssay Description:Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetWD repeat-containing protein 5(Homo sapiens (Human))
Propellon Therapeutics

US Patent
LigandPNGBDBM525582(US11174250, Example 32 | US11174250, Example Table...)
Affinity DataKd:  6nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20?? C. for repeat studies and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent