BDBM526271 2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- (rnethylamino)cyclohexyl) amino)isoindoline-1,3- dione::US11185537, Compound I-114

SMILES CN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=OKCAIIWEMWQKMS-PYNWJHIZSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 526271   

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526271(2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...)
Affinity DataEC50:  24nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM526271(2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-binding protein Ikaros(Homo sapiens)
Novartis

US Patent
LigandPNGBDBM526271(2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...)
Affinity DataEC50:  290nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent