BDBM526273 2-(2,6-dioxopiperidin-3-yl)-5-(((1S,2S)-2- (ethylamino)cyclohexyl)(methyl)amino) isoindoline-1,3-dione::US11185537, Compound I-104

SMILES CCN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=QCRHWBLMWLLUMA-UBFHEZILSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 526273   

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526273(2-(2,6-dioxopiperidin-3-yl)-5-(((1S,2S)-2- (ethyla...)
Affinity DataEC50:  49nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM526273(2-(2,6-dioxopiperidin-3-yl)-5-(((1S,2S)-2- (ethyla...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-binding protein Ikaros(Homo sapiens)
Novartis

US Patent
LigandPNGBDBM526273(2-(2,6-dioxopiperidin-3-yl)-5-(((1S,2S)-2- (ethyla...)
Affinity DataEC50:  51nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent