BDBM526282 5-(((1S,2S)-2- (dimethylamino)cyclohexyl)amino)-2-(2,6- dioxopiperidin-3-yl)isoindoline-1,3-dione::US11185537, Compound I-153

SMILES CN(C)[C@H]1CCCC[C@@H]1Nc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=IOSBUGPPJHKPFA-PYNWJHIZSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 526282   

TargetZinc finger protein Helios(Human)
Novartis

US Patent
LigandPNGBDBM526282(5-(((1S,2S)-2- (dimethylamino)cyclohexyl)amino)-2-...)
Affinity DataEC50:  410nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM526282(5-(((1S,2S)-2- (dimethylamino)cyclohexyl)amino)-2-...)
Affinity DataEC50: >5.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-binding protein Ikaros(Homo sapiens)
Novartis

US Patent
LigandPNGBDBM526282(5-(((1S,2S)-2- (dimethylamino)cyclohexyl)amino)-2-...)
Affinity DataEC50: >3.00E+4nMAssay Description:The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent