BDBM530435 7-Fluoro-6-(5-(2-hydroxypropan-2-yl)-1-methyl-1H-1,2,4-triazol-3-yl)-4-isopropyl- 2-(o-tolyl)isoquinolin-1(2H)-one.::WO2022070068, Example 29::WO2022070068, Example 7
SMILES CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1nc(n(C)n1)C(C)(C)O
InChI Key InChIKey=IIPLSPGUZDMYKL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 530435
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 0.640nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 0.570nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair