BDBM530456 6-(1-Ethyl-5-(1-hydroxyethyl)-1H-1,2,4-triazol-3-yl)-7-fluoro-4-isopropyl-2-(o- tolyl)isoquinolin-1(2H)-one.::WO2022070068, Example 28
SMILES CCn1nc(nc1C(C)O)-c1cc2c(cn(-c3ccccc3C)c(=O)c2cc1F)C(C)C
InChI Key InChIKey=VCTKNEDILZYCJC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530456
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 19nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair