BDBM530621 1-(5-(difluoromethoxy)-2-fluorophenyl)-3-(3-hydroxy-3-methylbutan-2-yl)-N-(3-methyl-1,1-dioxidothietan-3-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide::WO2022076495, EXAMPLE 65

SMILES CC(n1c2cc(ccc2n(-c2cc(OC(F)F)ccc2F)c1=O)C(=O)NC1(C)CS(=O)(=O)C1)C(C)(C)O

InChI Key InChIKey=FSPAFQBOWPGDDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 530621   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530621(1-(5-(difluoromethoxy)-2-fluorophenyl)-3-(3-hydrox...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human DGAT2 expressed in sf9 insect cell membrane assessed as reduction in 13C18-triolein product formation using 13C oleoyl-CoA as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM530621(1-(5-(difluoromethoxy)-2-fluorophenyl)-3-(3-hydrox...)
Affinity DataIC50:  0.700nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed