BDBM531991 N-{4-[2-Amino-5-(3,4-dimethoxyphenyl)pyridin-3-yl]-3-fluorophenyl}-5-(4-methylphenyl)-4-oxo-1-(tetrahydro-2H-pyran-4-ylmethyl)-1,4-dihydropyridine-3-carboxamide methanesulfonate::US11208403, Example 68

SMILES COc1ccc(cc1OC)-c1cnc(N)c(c1)-c1ccc(NC(=O)c2cn(CC3CCOCC3)cc(-c3ccc(C)cc3)c2=O)cc1F

InChI Key InChIKey=GEAJYTNNHUHUPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531991   

TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM531991(N-{4-[2-Amino-5-(3,4-dimethoxyphenyl)pyridin-3-yl]...)
Affinity DataIC50:  38nMAssay Description:A kinase dilution solution containing 20 ng/ml Mer (the 528th to 999th amino acids of the intracellular domain of human MER expressed as a fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM531991(N-{4-[2-Amino-5-(3,4-dimethoxyphenyl)pyridin-3-yl]...)
Affinity DataIC50:  0.600nMAssay Description:A kinase dilution solution containing 170 ng/ml AXL (the 464th to 885th amino acids of the intracellular domain of human AXL expressed as a fusion pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent