BDBM531994 N-[4-(2-Amino-5-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}pyridin-3-yl)phenyl]-5-(4-methylphenyl)-4-oxo-1-(tetrahydro-2H-pyran-4-ylmethyl)-1,4-dihydropyridine-3-carboxamide methanesulfonate::US11208403, Example 71

SMILES CN1CCN(Cc2ccc(cc2)-c2cnc(N)c(c2)-c2ccc(NC(=O)c3cn(CC4CCOCC4)cc(-c4ccc(C)cc4)c3=O)cc2)CC1

InChI Key InChIKey=IPHZKBACASVMHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 531994   

TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM531994(N-[4-(2-Amino-5-{4-[(4-methylpiperazin-1-yl)methyl...)
Affinity DataIC50:  64nMAssay Description:A kinase dilution solution containing 20 ng/ml Mer (the 528th to 999th amino acids of the intracellular domain of human MER expressed as a fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM531994(N-[4-(2-Amino-5-{4-[(4-methylpiperazin-1-yl)methyl...)
Affinity DataIC50:  0.600nMAssay Description:A kinase dilution solution containing 170 ng/ml AXL (the 464th to 885th amino acids of the intracellular domain of human AXL expressed as a fusion pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent