BDBM532954 US11214566, Compound (I-M7-2R,4S)
SMILES CC1(C)CCC(=CC1)c1nc(ccc1NC(=O)c1nc(c[nH]1)C#N)[C@H]1CC(C)(C)O[C@@](C)(CO)C1
InChI Key
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 532954
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 7.10nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Rattus norvegicus (Rat))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 9.60nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In this assay, recombinant human, dog or rat c-fms catalyzed the phosphorylation of the FMS peptide substrate, SYEGNSYTFIDPTQ, with the phosphorylate...More data for this Ligand-Target Pair