BDBM533728 US11225492, Compound 4-2

SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CC4CNCC(C3)C4(F)F)nc2n(C2CCCC2)c1=O

InChI Key InChIKey=QPRONZRNWIZACX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533728   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533728(US11225492, Compound 4-2)
Affinity DataIC50: <100nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533728(US11225492, Compound 4-2)
Affinity DataIC50: <50nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent