BDBM53448 1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidinyl]hydrazine::1-methyl-1-[4-(4-methylphenyl)-6-phenyl-pyrimidin-2-yl]diazane::1-methyl-1-[4-(4-methylphenyl)-6-phenylpyrimidin-2-yl]hydrazine::1-methyl-1-[4-phenyl-6-(p-tolyl)pyrimidin-2-yl]hydrazine::2-(1-methylhydrazino)-4-(4-methylphenyl)-6-phenylpyrimidine::MLS001001699::O-acyl oxime isatin derivative, 15::SMR000496236::cid_780059

SMILES CN(N)c1nc(cc(n1)-c1ccc(C)cc1)-c1ccccc1

InChI Key InChIKey=WYEPBQFKMXRABO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 53448   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53448(1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidi...)
Affinity DataIC50:  4.10E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53448(1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidi...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53448(1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidi...)
Affinity DataIC50:  1.13E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed