BDBM53467 1,3-Dimethyl-5-nitro-6-[2-(4-propoxy-phenyl)-vinyl]-1H-pyrimidine-2,4-dione::1,3-dimethyl-5-nitro-6-[(E)-2-(4-propoxyphenyl)ethenyl]pyrimidine-2,4-dione::1,3-dimethyl-5-nitro-6-[(E)-2-(4-propoxyphenyl)vinyl]pyrimidine-2,4-quinone::MLS001208899::O-acyl oxime isatin derivative, 50::SMR000518345::cid_5350691

SMILES CCCOc1ccc(\C=C\c2c([N+]([O-])=O)c(=O)n(C)c(=O)n2C)cc1

InChI Key InChIKey=KMYZLWWITDUFAG-JXMROGBWSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 53467   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53467(1,3-Dimethyl-5-nitro-6-[2-(4-propoxy-phenyl)-vinyl...)
Affinity DataIC50:  810nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53467(1,3-Dimethyl-5-nitro-6-[2-(4-propoxy-phenyl)-vinyl...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53467(1,3-Dimethyl-5-nitro-6-[2-(4-propoxy-phenyl)-vinyl...)
Affinity DataIC50:  1.70E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed