BDBM534787 US11230524, Compound ST119

SMILES COC(=O)NC(CCCCC(=O)Nc1ccccc1N)C(=O)Nc1cccc2cccnc12

InChI Key InChIKey=SZIUWBZVVUSRBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534787   

TargetHistone acetyltransferase p300/Myocyte-specific enhancer factor 2D(Homo sapiens (Human))
Standard

US Patent
LigandPNGBDBM534787(US11230524, Compound ST119)
Affinity DataIC50:  140nMAssay Description:Detection of MEF2D and P300 interactions. The same system that was used in Example 19 is used in here to detect MEF2D and P300 interactions. In this ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 4/Myocyte-specific enhancer factor 2D(Homo sapiens (Human))
Standard

US Patent
LigandPNGBDBM534787(US11230524, Compound ST119)
Affinity DataIC50:  390nMAssay Description:Detection of MEF2D and HDAC4 interactions. In this mammalian two-hybrid assay, HDAC4 and MEF2D proteins were used. Two separate DNA constructs were m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent