BDBM53480 1-(3-tert-Butylsulfanyl-[1,2,4]thiadiazol-5-yl)-3-(3-methoxy-phenyl)-urea::1-(3-tert-butylsulfanyl-1,2,4-thiadiazol-5-yl)-3-(3-methoxyphenyl)urea::1-[3-(tert-butylthio)-1,2,4-thiadiazol-5-yl]-3-(3-methoxyphenyl)urea::MLS001205986::O-acyl oxime isatin derivative, 61::SMR000504723::cid_24746846

SMILES COc1cccc(NC(=O)Nc2nc(SC(C)(C)C)ns2)c1

InChI Key InChIKey=MPCYMWBLAGJBNJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 53480   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53480(1-(3-tert-Butylsulfanyl-[1,2,4]thiadiazol-5-yl)-3-...)
Affinity DataEC50:  9.69E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mus musculus (Mouse))
Brigham and Women'S Hospital

LigandPNGBDBM53480(1-(3-tert-Butylsulfanyl-[1,2,4]thiadiazol-5-yl)-3-...)
Affinity DataIC50:  1.60E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed