BDBM535569 (R)-5-(3-morpholino-5- ((tetrahydrofuran-3- yl)sulfonyl)phenyl)-4- (trifluoromethyl)thiazol-2-amine::US11236079, Example 2
SMILES Nc1nc(c(s1)-c1cc(cc(c1)S(=O)(=O)[C@@H]1CCOC1)N1CCOCC1)C(F)(F)F
InChI Key InChIKey=LPFXPIMUHAZPRX-CYBMUJFWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 535569
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 740nMAssay Description:Compounds were prepared at 100× final concentration using a 12-point, 1:3 serial-dilution in DMSO, with DMSO control as the 12th point. Compound was ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 2.10E+3nMAssay Description:The substrate (Phosphatidylinositol (PI): Phosphatidylserine (PS)) was added to freshly prepared reaction buffer (40 mM Tris-HCl (pH7.5), 3 μM O...More data for this Ligand-Target Pair