BDBM535614 5-(3-morpholino-5- (phenylsulfonyl)phenyl)-1,2,4- thiadiazol-3-amine::US11236079, Example 4
SMILES Nc1nsc(n1)-c1cc(N)cc(c1)S(=O)(=O)c1ccccc1
InChI Key InChIKey=VGXXWIIGXVMSTG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 535614
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 1.12E+4nMAssay Description:Compounds were prepared at 100× final concentration using a 12-point, 1:3 serial-dilution in DMSO, with DMSO control as the 12th point. Compound was ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 2.20E+3nMAssay Description:The substrate (Phosphatidylinositol (PI): Phosphatidylserine (PS)) was added to freshly prepared reaction buffer (40 mM Tris-HCl (pH7.5), 3 μM O...More data for this Ligand-Target Pair