BDBM535714 5-(6-morpholino-4- phenoxypyridin-2-yl)thiazol-2- amine::US11236079, Example 8
SMILES Nc1ncc(s1)-c1cc(Oc2ccccc2)cc(n1)N1CCOCC1
InChI Key InChIKey=OVMCQYGOXYQBOT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 535714
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 3.42E+3nMAssay Description:Compounds were prepared at 100× final concentration using a 12-point, 1:3 serial-dilution in DMSO, with DMSO control as the 12th point. Compound was ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Neuropore Therapies
US Patent
Neuropore Therapies
US Patent
Affinity DataIC50: 150nMAssay Description:The substrate (Phosphatidylinositol (PI): Phosphatidylserine (PS)) was added to freshly prepared reaction buffer (40 mM Tris-HCl (pH7.5), 3 μM O...More data for this Ligand-Target Pair