BDBM536875 2-cyano-N-methyl-3-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl)-1-(tetrahydro-2H-pyran-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridine-5(4H)-carboxamide::US11247989, Example 49

SMILES CNC(=O)N1CCc2c(C1)c(c(C#N)n2C1CCOCC1)-c1cccc2cc(ncc12)-c1cnn(C)c1

InChI Key InChIKey=FHDSEZXJVYUDBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 536875   

TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM536875(2-cyano-N-methyl-3-(3-(1-methyl-1H-pyrazol-4-yl)is...)
Affinity DataIC50:  1.42nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent