BDBM537770 US11248001, Example 177::US11603523, Example 177

SMILES COc1ccc(CNS(=O)(=O)c2ccc3nc(NCC(CNc4ncc(SC)cn4)CC(N)=O)sc3c2)cc1

InChI Key InChIKey=HICODQYXRYMYAS-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 537770   

TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM537770(US11248001, Example 177 | US11603523, Example 177)
Affinity DataKd:  1.10E+4nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CM5 (GE Hea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM537770(US11248001, Example 177 | US11603523, Example 177)
Affinity DataKd:  1.10E+4nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CMS (GE Hea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent