BDBM537786 US11248001, Example 205::US11603523, Example 205

SMILES CSc1cnc(NC[C@H](C)CNc2ccc(cn2)[C@H]2C[C@@H]2C(=O)N2CCC3(CN(C)C3)CC2)nc1

InChI Key InChIKey=ZYJXTZATSABJCQ-QIJUGHKUSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 537786   

TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM537786(US11248001, Example 205 | US11603523, Example 205)
Affinity DataKd:  1.10E+3nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CM5 (GE Hea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM537786(US11248001, Example 205 | US11603523, Example 205)
Affinity DataKd:  1.10E+3nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CMS (GE Hea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent