BDBM542553 (S)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3- b]pyridin-6-yl)-2-methylbut-3-yn-2-amine::(S)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine::US11274108, Example 1-5-enant-A

SMILES COc1ccc(cn1)[C@@H]1COc2cc(Cn3cnc4cc(cnc34)C#CC(C)(C)N)ccc2O1

InChI Key InChIKey=DRBFONOVLOXKJM-QHCPKHFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542553   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM542553((S)-4-(3-((2-(6-methoxypyridin-3-yl)-2,3- b]pyridi...)
Affinity DataIC50:  6nMAssay Description:All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...More data for this Ligand-Target Pair
In DepthDetails US Patent