BDBM542791 (S)-6-(difluoromethyl)-3-((8-methoxy-2-(6-methoxypyridin- imidazo[4,5-b]pyridine::(S)-6-(difluoromethyl)-3-((8-methoxy-2-(6-methoxypyridin-3-yl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5-b]pyridine::US11274108, Example 1-86-enant-A

SMILES COc1ccc(cn1)[C@H]1COc2cc(Cn3cnc4cc(cnc34)C(F)F)cc(OC)c2O1

InChI Key InChIKey=NNALMBBVMICMFI-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542791   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM542791((S)-6-(difluoromethyl)-3-((8-methoxy-2-(6-methoxyp...)
Affinity DataIC50:  4nMAssay Description:All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent