BDBM542855 4-(3-((2-(4-(difluoromethoxy)phenyl)-8-methoxy-2,3- dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5- b]pyridin-6-yl)-2-methylbut-3-yn-2-amine::4-(3-((2-(4-(difluoromethoxy)phenyl)-8-methoxy-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine::US11274108, Example 1-139

SMILES COc1cc(Cn2cnc3cc(cnc23)C#CC(C)(C)N)cc2OCC(Oc12)c1ccc(OC(F)F)cc1

InChI Key InChIKey=ZFJSNFWTQYPMOE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542855   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM542855(4-(3-((2-(4-(difluoromethoxy)phenyl)-8-methoxy-2,3...)
Affinity DataIC50:  7nMAssay Description:All assay reaction conditions for IC50 determinations were within the linear range with respect to time and enzyme concentration. In a 384 well polyp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent