BDBM543455 US11279699, Compound Example 6

SMILES CCS(=O)(=O)C1CN(Cc2ccc(cc2)-c2cccc3nc(NC(=O)C(C)C)nn23)C1

InChI Key InChIKey=INAPHNCKKRHWSH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 543455   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543455(US11279699, Compound Example 6)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543455(US11279699, Compound Example 6)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543455(US11279699, Compound Example 6)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent