BDBM543477 2-((6-chloro-5-(2'-hydroxy-4'-(1H-1,2,4- triazol-1-yl)-[1,1'-biphenyl]-4-yl)-1H- imidazo[4,5-b]pyridin-2-yl)thio)acetic acid::US11279702, Compound 9

SMILES OC(=O)CSc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1O)-n1cncn1

InChI Key InChIKey=UBPFDENNZKYJDP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543477   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Kallyope

US Patent
LigandPNGBDBM543477(2-((6-chloro-5-(2'-hydroxy-4'-(1H-1,2,4- triazol-1...)
Affinity DataEC50:  1.10nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent