BDBM54584 1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-propanone::1-[4-(2,5-dimethylphenyl)piperidin-1-yl]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propan-1-one::1-[4-(2,5-dimethylphenyl)piperidino]-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propan-1-one::KUC103432N::UNM-0000306151::cid_44143707

SMILES COc1ccc(cc1)-c1noc(CCC(=O)N2CCC(CC2)c2cc(C)ccc2C)n1

InChI Key InChIKey=LRUFYTMGSXHKFO-UHFFFAOYSA-N

Data  6 KI  8 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 54584   

TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataKi:  90nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataKi:  110nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataKi:  230nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataKi:  250nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataKi:  300nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  1.42E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  2.51E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  1.63E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  1.22E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  2.50E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54584(1-[4-(2,5-dimethylphenyl)-1-piperidinyl]-3-[3-(4-m...)Copy SMILESCopy InChI

Affinity DataEC50:  1.33E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI