BDBM54676 (3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxindole::(3Z)-3-(5-oxidanylidene-2-sulfanylidene-imidazolidin-4-ylidene)-1H-indol-2-one::(3Z)-3-(5-oxo-2-sulfanylidene-4-imidazolidinylidene)-1H-indol-2-one::(3Z)-3-(5-oxo-2-sulfanylideneimidazolidin-4-ylidene)-1H-indol-2-one::UNM-0000305762::cid_5339891

SMILES O=C1NC(=S)N\C1=C1/C(=O)Nc2ccccc12

InChI Key InChIKey=FLGULZIWPBCRTB-FPLPWBNLSA-N

Data  3 KI  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 54676   

LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataKi:  640nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataKi:  870nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  1.34E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  7.00E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  1.67E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54676((3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxi...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay