BDBM54690 2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophenyl)sulfonyl-3-pyrrolecarbonitrile::2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophenyl)sulfonylpyrrole-3-carbonitrile::2-amino-5-benzoyl-4-(4-chlorophenyl)-1-nosyl-pyrrole-3-carbonitrile::2-azanyl-4-(4-chlorophenyl)-1-(4-nitrophenyl)sulfonyl-5-(phenylcarbonyl)pyrrole-3-carbonitrile::UNM-0000305780::cid_25220931

SMILES Nc1c(C#N)c(c(C(=O)c2ccccc2)n1S(=O)(=O)c1ccc(cc1)[N+]([O-])=O)-c1ccc(Cl)cc1

InChI Key InChIKey=DMRRVOKZYZBWDZ-UHFFFAOYSA-N

Data  3 KI  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 54690   

LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataKi:  540nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataKi:  930nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataKi:  1.52E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  7.21E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  5.93E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM54690(2-amino-5-benzoyl-4-(4-chlorophenyl)-1-(4-nitrophe...)
Affinity DataEC50:  5.98E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay