BDBM547727 US11292792, CMPD # I-57

SMILES CC(C)(C)OC(=O)NCCOCCOCCCc1ccnc2n(C3CCC(=O)NC3=O)c3ccccc3c12

InChI Key InChIKey=JLEJQFBYSQLXKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547727   

TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Kymera Therapeutics

US Patent
LigandPNGBDBM547727(US11292792, CMPD # I-57)
Affinity DataIC50: <10nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent