BDBM547741 US11292792, CMPD # I-71

SMILES CC(C)(C)OC(=O)NC1CCN(CCc2ccc3n(C4CCC(=O)NC4=O)c4ncccc4c3c2)CC1

InChI Key InChIKey=PTWWJNVIOCJABF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547741   

TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Kymera Therapeutics

US Patent
LigandPNGBDBM547741(US11292792, CMPD # I-71)
Affinity DataIC50: <10nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent