BDBM549227 US11299493, Compound 1.143::US11299493, Compound 1.147::US11299493, S-46

SMILES CC(C)(C)c1cccc(n1)-n1n(C2CC2)c(=O)c2cnc(Nc3ccc4CNCCc4c3)nc12

InChI Key InChIKey=IWUUJTQUOOCTGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549227   

TargetWee1-like protein kinase(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM549227(US11299493, Compound 1.143 | US11299493, Compound ...)
Affinity DataIC50:  7nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetWee1-like protein kinase(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM549227(US11299493, Compound 1.143 | US11299493, Compound ...)
Affinity DataIC50:  3nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent