BDBM550778 (3R,4R) and (3S,4S)-2-[4-(1- acetylpiperidin-4-yl)-3-rnethylphenyl]- 3-(2,3-dihydro-1,4-benzodioxin-6-yl)- 1-oxo-1,2,3,4-tetrahydroisoquinoline-4- carboxylic acid::US11311528, Ex. 1-68
SMILES CC(=O)N1CCC(CC1)c1ccc(cc1C)N1[C@H]([C@H](C(O)=O)c2ccccc2C1=O)c1ccc2OCCOc2c1
InChI Key InChIKey=YAOUNJRPXSKTEF-IHLOFXLRSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 550778
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.47E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair