BDBM551163 3-(7-Bromo-1H-indazol-5-yl)-2-(difluoromethyl)-5-(trifluoromethyl)imidazo[4,5-::US11312712, Example 280
SMILES FC(F)c1nc2ccc(nc2n1-c1cc(Br)c2[nH]ncc2c1)C(F)(F)F
InChI Key InChIKey=MJTNQSTWFFYACY-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 551163
TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 0.0160nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair