BDBM551163 3-(7-Bromo-1H-indazol-5-yl)-2-(difluoromethyl)-5-(trifluoromethyl)imidazo[4,5-::US11312712, Example 280

SMILES FC(F)c1nc2ccc(nc2n1-c1cc(Br)c2[nH]ncc2c1)C(F)(F)F

InChI Key InChIKey=MJTNQSTWFFYACY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551163   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM551163(3-(7-Bromo-1H-indazol-5-yl)-2-(difluoromethyl)-5-(...)
Affinity DataIC50:  0.0160nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent