BDBM552252 (13S,21aR,Z)-13-ethyl-16-hydroxy-6,10,13,21a-tetrahydro-7,8-(epiprop[1]en[1]yl[3]ylidene)-14,21-methanobenzo[6,7]thiepino[4,5-c]pyrido[1,2-f][1]oxa[5,6,9]triazacyclotridecine-15,17-dione (Compound 92AA)::US11312727, Compound 92BA

SMILES CC[C@H]1\C=C\COc2cccc3CSc4ccccc4[C@@H](N4CN1C(=O)c1c(O)c(=O)ccn41)c23

InChI Key InChIKey=GEKXPSVNGAPZTI-REKSSAIRSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552252   

TargetPolymerase basic protein 2(Influenza A virus (strain A/WS/1933 H1N1))
Janssen Biopharma

US Patent
LigandPNGBDBM552252((13S,21aR,Z)-13-ethyl-16-hydroxy-6,10,13,21a-tetra...)
Affinity DataIC50:  11nMAssay Description:EN PA FRET inhibition assay was performed using a 19 nucleotide synthetic oligoribonucleotide substrate: 5′-FAM-AUUUUGUUUUUAAUAUUUC-BHQ-3′...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase basic protein 2(Influenza A virus (strain A/WS/1933 H1N1))
Janssen Biopharma

US Patent
LigandPNGBDBM552252((13S,21aR,Z)-13-ethyl-16-hydroxy-6,10,13,21a-tetra...)
Affinity DataEC50:  0.700nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent