BDBM552406 (9*R,17a*R,*E)-24,25-difluoro-12-hydroxy-9-methyl-2,6,9,17a-tetrahydro-3,4-(epiprop[1]en[1]yl[3]ylidene)-10,17-methanobenzo[6,7]thiepino[4,5-c]pyrido[1,2-f][1]oxa[5,6,9]triazacyclotridecine-11,13-dione (Compound 162A)::US11312727, Compound 162D

SMILES C[C@H]1\C=C/COc2cc(F)c(F)c3CSc4ccccc4C(N4CN1C(=O)c1c(O)c(=O)ccn41)c23

InChI Key InChIKey=QDCFBZXTHKHIFC-PZPVRXHTSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552406   

TargetPolymerase basic protein 2(Influenza A virus (strain A/WS/1933 H1N1))
Janssen Biopharma

US Patent
LigandPNGBDBM552406((9*R,17a*R,*E)-24,25-difluoro-12-hydroxy-9-methyl-...)
Affinity DataIC50:  2nMAssay Description:EN PA FRET inhibition assay was performed using a 19 nucleotide synthetic oligoribonucleotide substrate: 5′-FAM-AUUUUGUUUUUAAUAUUUC-BHQ-3′...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase basic protein 2(Influenza A virus (strain A/WS/1933 H1N1))
Janssen Biopharma

US Patent
LigandPNGBDBM552406((9*R,17a*R,*E)-24,25-difluoro-12-hydroxy-9-methyl-...)
Affinity DataEC50:  0.510nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent