BDBM552430 US11312727, Compound 171A

SMILES Cc1cccnc1[C@H]1N2CN(C(=O)c3c(O)c(=O)ccn23)C2(CCC2)\C=C\COc2c(F)c(F)ccc12

InChI Key InChIKey=WJNNRDALHBLDJN-NHTJFMIFSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552430   

TargetPolymerase basic protein 2(Influenza A virus (strain A/WS/1933 H1N1))
Janssen Biopharma

US Patent
LigandPNGBDBM552430(US11312727, Compound 171A)
Affinity DataIC50:  8.30nMAssay Description:EN PA FRET inhibition assay was performed using a 19 nucleotide synthetic oligoribonucleotide substrate: 5′-FAM-AUUUUGUUUUUAAUAUUUC-BHQ-3′...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase basic protein 2(Influenza A virus (strain A/WS/1933 H1N1))
Janssen Biopharma

US Patent
LigandPNGBDBM552430(US11312727, Compound 171A)
Affinity DataEC50:  1.30nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent