BDBM552966 4-(difluoromethyl)-N-[4- fluoro-2-(4-methylpiperazin- 1-yl)-5-(2-morpholin-4- ylpyrimidin-5-yl)phenyl]- 6-oxo-1H-pyridine-3- carboxamide::US11319299, Example 20
SMILES CN1CCN(CC1)c1cc(F)c(cc1NC(=O)c1c[nH]c(=O)cc1C(F)F)-c1cnc(nc1)N1CCOCC1
InChI Key InChIKey=UJCBRBGSYIDHKB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 552966
Affinity DataKd: 2nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...More data for this Ligand-Target Pair