BDBM556230 US11345699, Example 113

SMILES COc1cc2CCN(Cc2cc1C(=O)Nc1cccc(n1)-c1nnnn1[C@H](C)CO)C(=O)[C@@H](O)CC(C)C

InChI Key InChIKey=CXDMJDYWKDAZBR-IERDGZPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 556230   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM556230(US11345699, Example 113)
Affinity DataIC50: <1.25nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue #PV4011), ATP was purchased from Sigma (Catalogue #A7699), HTRF® KinEASE Assay System was obtained fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Enanta Pharmaceuticals

US Patent
LigandPNGBDBM556230(US11345699, Example 113)
Affinity DataIC50: <1.25nMAssay Description:ASK1 was purchased from Thermofisher (Catalogue #PV4011), ATP was purchased from Sigma (Catalogue #A7699), HTRF® KinEASE Assay System was obtained fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent