BDBM556326 1-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)pyrimidin-2-ylamino)pyridin-3-yl)methyl)piperazin-1-yl)-2-hydroxyethanone (Compound 22)::US11351170, Example 2
SMILES CC1(C)CCc2nc3c(F)cc(cc3n12)-c1nc(Nc2ccc(CN3CCN(CC3)C(=O)CO)cn2)ncc1F
InChI Key InChIKey=FMYDWZBWZKJPCK-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 556326
Affinity DataIC50: 0.730nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 79.9nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 8.84nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair