BDBM5573 6-(benzyloxy)-5-nitrosopyrimidine-2,4-diamine::CHEMBL71484::pyrimidine deriv. 1g

SMILES Nc1nc(N)c(N=O)c(OCc2ccccc2)n1

InChI Key InChIKey=MBQPVHNJEDDVCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5573   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5573(6-(benzyloxy)-5-nitrosopyrimidine-2,4-diamine | CH...)
Affinity DataIC50:  2.70E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM5573(6-(benzyloxy)-5-nitrosopyrimidine-2,4-diamine | CH...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Newcastle

LigandPNGBDBM5573(6-(benzyloxy)-5-nitrosopyrimidine-2,4-diamine | CH...)
Affinity DataIC50:  2.70E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed