BDBM558236 N-[6-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxy]hexyl]methanesulfonamide::US11365192, Example 19-1

SMILES CS(=O)(=O)NCCCCCCOc1ccc(nc1)-c1ccn[nH]1

InChI Key InChIKey=KARZCKAGWYTWDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558236   

TargetCytochrome P450 4A11(Homo sapiens)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558236(N-[6-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxy]hexyl]m...)
Affinity DataIC50:  1.70E+3nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 4F2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558236(N-[6-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxy]hexyl]m...)
Affinity DataIC50:  22nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent