BDBM558727 Isomer-1 of 4-((3-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-4,4-::US11365205, Example 2a

SMILES CC1(C)CN(Cc2ccc(cc2)C#N)C(=O)N1C[C@H](O)CN1CCc2ccccc2C1

InChI Key InChIKey=CFWIOFLDKMVDHR-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558727   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM558727(Isomer-1 of 4-((3-(3-(3,4-dihydroisoquinolin-2(1H)...)
Affinity DataIC50:  40nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent